T.R. Knight as George Se no’Malley
One of the biggest tearjerkers this list, at the end of season five, George had just decided to enlist as a contusione surgeon the army and was his way to do so when he saved a woman from getting successo by a bus, only to be successo himself. He was such bad shape when he got to the hospital that one recognized him until he used his finger to write his nickname, 007, Meredith’s hand. They were unable to save him, and he tragically died.
After several tumultuous seasons behind the scenes (including Isaiah Washington using the f-word while allegedly referring to him), Knight struggled with some of George’s storylines and the fact that George barely appeared the beginning of season five, and asked to be released from his contract.
Knight returned to Shondaland 2017 for an arc The Catch, and has also appeared The Good Wife, 11.22.63, and Genius, among other series. Con 2019, he appeared The Bravest Knight and 2020, he appeared HBO Max series The Flight Attendant with Kaley Chef. He also returned to Grey’s for one episode to meet Meredith during her COVID-19 coma.
